Ipamorelin vs Sermorelin, Which is Better?

31Janipamorelin vs sermorelin

Most people look forward to when they will become grown-ups. As much as being a grown-up comes with a fair share of perks, once you start aging, some aspects of your body start changing. For instance, the production of peptides responsible for the structural integrity of proteins might slow down. This might result in saggy skin, weakening of the joints, loss of muscle mass, to mention but a few.

This is the point where artificial peptides such as Ipamorelin and Sermorelin can be introduced into the body to boost the generation of growth hormones. Ipamorelin and Sermorelin play a key role in boosting the functioning of specific receptors that aid in the synthesis of growth hormones. The rise in growth hormones within the body in most cases reverses the aging pains that might have started taking effect in the body. The growing pains might include joint inflammation, increased fat deposits, decreased libido, slow healing of wounds, and brittle bones.

The two peptides are quite similar but that doesn’t mean they don’t have their differences. Sermorelin can be considered somewhat whole rounded as it plays many roles but when compared to Ipamorelin it falls short. Ipamorelin is way more potent than its counterpart. It is very effective and plays a crucial role in boosting the efficiency of peptide therapy.

With that said, getting a deeper understanding of the two peptides helps in knowing which one can be more suited in catering to your needs.

In summary, Ipamorelin is a more modern and “cleaner” GHRH therapy. Currently, it’s the one offered first by most anti-aging clinics to help increase your IGF-1 levels. For details, read more below!

Ipamorelin

As much as both peptides help in the secretion of growth hormones they tend to affect the receptors differently. When it comes to Ipamorelin it is known as a five amino acid chain. It was initially termed as a secretagogue which means something that promotes secretion.

Ipamorelin works hand in hand with the ghrelin receptors which are situated at the pituitary gland. Ghrelin is naturally found within the body but its production tends to fluctuate due to several reasons. Once Ipamorelin is in the body it mimics the human growth hormone, ghrelin. The good thing is that the process is almost instantaneous.

Once the Ipamorelin is introduced to the system significant changes can be felt within a short period, usually between 5 to 15 minutes. The treatment is introduced into the body in 3 main ways, often chosen based on an individual’s preference. These include injections, oral and nasal administration.

Benefits

While the body benefits immensely from Ipamorelin treatments, the results are also linked to the peptide’s impact on your appetite. Based on what you eat, a couple of advantages arise from the improved diet. Here is a quick rundown of those benefits:

  • Gain and Maintain Muscle Mass
  • Boost in Immunity
  • Better Metabolism
  • Anti-aging
  • Improved bone density
  • Increased Energy
  • Improves Alertness
  • Promote joint health
  • Muscle recovery
  • Better sleep

Dosage

For you to reap the optimum benefits of this kind of peptide, you need to follow the dosage properly. Dosages in every situation are extremely important for two main reasons: One you don’t want to overdo it and two, you need the right dosage to experience the most effective results.

When it comes to Ipamorelin you can get it in various forms such as pills, nasal sprays, and subcutaneous injections.

The dosage in this segment is more tailored to the use of the subcutaneous injection form. The most common prescription, in this case, is usually an injection of 150mcg. Also, the administration needs to be done at the exact time every day. The injections are to be done around the abdominal area as it helps in the effects of the peptide.

In the case where the prescription includes other peptides in conjunction with Ipamorelin, the dosage of Ipamorelin remains the same. But you are always advised to pair it with peptides that work together and not against it. Something like CJC-1295 is the most common peptide used with Ipamorelin.

Uses

Ipamorelin can be used for several defects, disorders, and ailments that might be affecting you. It can be used to:

  • Improve appetite
  • Improve brain function. The peptide provides help in supporting the storage of memory and enhances learning
  • Helps in losing fat and building leaner muscles
  • treat osteoporosis as it improves the density and composition of the bones
  • Improve the structure of collagen, hence the improvement of the skin condition.
  • Relieve pain. The correlations between food and pain are quite intriguing. The intake of food tends to cloud the way pain is perceived so the smoother the intake the less likely you will be susceptible to experience pain in general

Side Effects

The side effects are quite minimal when it comes to Ipamorelin but don’t take that to mean that they are nonexistent. These are some of the symptoms that you might experience as you use the peptide.

Irritation and Redness

This occurs majorly near the injection site. This symptom starts to manifest when your body tries to counteract the new routine. Once the body gets used to it, the redness clears up and the irritation seizes.

Increased Appetite

This isn’t such a bad thing but it is worth noting. It comes about as you continue building and gaining muscle mass.

Nausea and Dry Mouth

This can be quite irritating in the first stages but you will get used to it. It’s a small sacrifice to reap the most benefit out of the peptide regiment.

While most of the time the above symptoms can be mild, don’t ignore them if they become unbearable. If they make you extremely uncomfortable then it would be advisable to seek an expert opinion from a medical professional.

Sermorelin

This type of peptide has 29 amino acids stringed together in a chain. It mimics the effects and functions of growth hormone-releasing hormone(GHRH). It is considered a baseline peptide that can be used to introduce people into the world of peptide therapy. It works just like Ipamorelin by stimulating the pituitary gland to release more growth hormones.

Benefits

The benefits of Sermorelin are brought about by the GHRH that is presented in the body once the peptide stimulates the pituitary gland. The following is a list of common benefits of this peptide;

  • Anti-aging
  • Bone cell generation
  • Burning of fats
  • Building of muscle mass
  • Causes angiogenesis
  • Better sleep
  • Strength immune system
  • Healthy skin
  • Increased hair volume

Dosage

There are two different ways by which you can take Sermorelin, and the most common one is the use of injectables. Just like Ipamorelin, it’s a subcutaneous injection. The injection is conducted by the use of a small syringe around the abdominal area. The injections are done five nights a week and have to be made two hours after your last meal of the day. Any sugar consumed within that time might interrupt the dosage.

The other method of intake is the use of the oral passage where the use of mint-sized pills is most common. They are not chewed or directly swallowed, instead, they are placed at the inner lining of the cheek to allow absorption into the bloodstream. The pills are typically used to correct deficiencies of serotonin or dopamine.

Uses

The Sermorelin can work wonders within the body and it has been used by experts to cater to several issues in the body. A sermorelin peptide treatment helps to;

  • Correct osteoporosis with the bone cell generation attributes
  • Solve short-term memory issues. It helps with neurogenesis
  • Upregulate mesenchymal stem cell production
  • Improve the health and condition of the skin by promoting collagen production
  • Improve the regeneration of hair cells. The hair strands become stronger and thicker

Side Effects

Sermorelin causes a series of side effects, some of which you might need to seek medical attention. For example, hives, difficulty in breathing, pain, redness, or swelling of the injected area, rash, and swelling of the tongue, face, lips, and mouth. That aside, let’s look further into the different side effects exhibited by the peptide.

Production of GRF

The production of GRF might affect the production of certain antibodies. The antibodies that arise from the introduction of Sermorelin might resolve themselves with time without the need for medical interventions.

Redness and Irritation

By use of the injection option, the area being injected might become reddish over time but it will also clear up on its own once the body gets used to the dosage. The area where the needle pricks the skin might be bumpy and a little painful to touch. On the good side, this too gets better over time.

Development of Hives

This doesn’t occur that often but it’s worth mentioning. In most cases, this is a result of an allergic reaction to the introduction of Sermorelin into the system. It appears in the area where the shot is administered but it can also spread further.

Hyperactivity

While some patients get drowsy after the intake of Sermorelin, others experience the complete opposite. A good percentage finds it a little hard to concentrate with feelings of restlessness which can be referred to as hyperactivity. This is normally a result of taking a higher dose than what is required.

Change in Blood Glucose Levels

For a short while after the first shot, the patient experiences insulin resistance. This explains why you are advised to take the shot before going to bed.

Headaches

The intensity of the headache might vary. But if it gets a little too intense then you should seek medical advice from your physician to discuss dose change or a counteracting drug to cater to the side effect.

Which is Better?

The question might be a little hard to answer because they are closely related to one another but here are a few things that you can look out for.

Sermorelin, when compared to Ipamorelin, you will notice it has no specific hormone that it aims at fixing. Sermorelin is a general form of GHRH while Ipamorelin tends to mimic Ghrelin which directly affects how you feel on the account of your food consumption and metabolism.

The other reason as to why Ipamorelin might have an upper hand when compared to Sermorelin is the manufacturing process of the drug. The active ingredients of the Sermorelin have become somewhat hard to procure making it different from one manufacturer to the other.

This has made it hard for it to be used by most physicians due to the instability. As a result, the drug has been withdrawn from the market to safeguard the medical practice of most health providers. So to say, Ipamorelin is better than Sermorelin when it comes to both safety and efficacy.

How to Get Ipamorelin

When looking for a reliable provider of peptides, where do you go? How do you know who to trust? What is the process that you need to follow? It comes naturally that you need a well-established anti-aging clinic that can cater to all your needs. 

By visiting an anti-aging clinic you are not directly strapped into a bed and the treatment starts. A rigorous process needs to follow:

Blood Test for Growth Hormone Deficiency

The bloodwork helps in pinpointing the exact levels of growth hormones in the blood. And because growth hormone secretion occurs in the pituitary gland, blood testing helps in understanding whether the cause of the deficiency has something to do with the gland.

More Exams

Additional body exams are conducted to establish what the problem is. For instance, MRIs and X Rays might be done to ascertain that it’s hormone deficiency and not age-related retrogradation of the body.

Treatment of Growth Hormones Deficiency

Once the physician is sure that the body needs a boost in growth hormones then they might put you under peptide therapy. In this case administration of Ipamorelin will take place. A daily injection of the peptide is recommended for optimal results.

Depending on the age and other factors, the dosage might vary from one client to the other. Physicians will always be on high alert to ensure there is steady progress. In most cases, within 6 months there is usually an improvement of about 35%.

Winding Up…

For obvious reasons, the benefits of getting peptide therapy outweigh any of the cons listed above. However, there are always some skeptics out there. The only way you can ensure you get the best treatment is by seeking proper medical advice.

Peace of mind is what any potential medical service clientele would always want. The task of seeking a trustworthy anti-aging clinic that uses only FDA-approved medication can be daunting. At Prolong labs, we ensure that you get to be paired with the most suitable clinic with the best services.

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